Cell line development is the process of using the cellular machinery to produce therapeutic biologics or other desired proteins. Numerous expression methods, including bacterial, plant-based, yeast, and mammalian ones, can be used for cell line generation. The most commonly used cells for producing complex proteins are Chinese hamster ovary (CHO) cells, which are cultivated in suspension cultures with the ultimate goal of being used in bioreactors during the manufacturing stage. Gene editing has been improved in recent years by molecular tools like as transcription activator-like effector nucleases (TALENs), zinc finger nucleases (ZFN), and, most recently, the CRISPR/Cas9 system. These methodologies have significantly improved accuracy and convenience of use when developing cell lines for maximum biotherapeutic output.
Top Key Players Covered in Cell Line Development Market
GE Healthcare, Sartorious AG, Corning Inc., WuXi AppTec Inc., Selexis SA, Sigma-Aldrich Corporation, Lonza Group AG, Sartorius, Thermo Fisher Scientific Inc., Danaher Corporation, Merck KGaA, Promega Corporation, Beckman Coulter Inc., European Collection of Cell Cultures, and Other Major Players.
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An in-depth examination of the overall Cell Line Development industry is done to provide this market report encompassing all essential market fundamentals. Our findings are built upon a solid foundation, drawing from a wide range of primary and secondary sources. To further enhance the comprehensiveness of our evaluation, we employ industry-standard tools such as Porter's Five Forces Analysis, SWOT Analysis, and Price Trend Analysis.
Segmentation Analysis of the Cell Line Development Market
By Product
- Equipment
- Reagents & Media
- Accessories & Consumables
By Source
- Mammalian
- Non-Mammalian
By Cell Line Type
- Recombinant Cell Lines
- Hybridomas
- Continuous Cell Lines
- Primary Cell Lines
By Application
- Bioproduction
- Drug Discovery
- Toxicity Testing
- Tissue Engineering
- Research
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Regional Analysis Of the Cell Line Development Market
During the projected period, the cell line development market is expected to be dominated by the North American region. The use of cell lines in the development of novel treatment approaches has been aided by the rising incidence of cancer and seasonal flu. The American Cancer Society projects that in 2021 there will be 1.9 million new instances of cancer diagnosed. An estimated 608,570 Americans will die from cancer in 2021, or about 1,670 people every day. Heart disease is the leading cause of death in the United States, with cancer coming in second. Basic models used in labs to investigate cancer biology and the therapeutic efficacy of anticancer drugs are human cancer-derived cell lines. HeLa was the first cancer line to be cultivated.
By Region
- North America (US, Canada, Mexico)
- Eastern Europe (Bulgaria, The Czech Republic, Hungary, Poland, Romania, Rest of Eastern Europe)
- Western Europe (Germany, UK, France, Netherlands, Italy, Russia, Spain, Rest of Western Europe)
- Asia Pacific (China, India, Japan, South Korea, Malaysia, Thailand, Vietnam, The Philippines, Australia, New Zealand, Rest of APAC)
- Middle East & Africa (Turkey, Bahrain, Kuwait, Saudi Arabia, Qatar, UAE, Israel, South Africa)
- South America (Brazil, Argentina, Rest of SA)
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