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The CYP450 family of enzymes is responsible for metabolizing several cannabinoids, including CBD, research shows. Specifically, CYP3A4, an important enzyme within the CYP450 family, does the task. A family of enzymes called cytochrome P450 does the important work of converting foreign substances so they can easily be eliminated from the body. When you take a medication or other substance, your body has to metabolize it, or break it down.
But you could still have a problem if your cannabis product was contaminated with THC, Fitzgerald said. Licensed farmers can now grow the plant, as long as it contains less than 0.3% THC. CBD is turning up in everything from oils and lotions to coffee and cookies.
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