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As one of the global leading biotechnology companies, Creative Biogene is able to offer the dedicated service for the synthesis of GMP-grade mRNAs to customers worldwide. With our unparalleled expertise and experience in mRNA synthesis and the comprehensive QC and QA program, Creative Biogene is available to produce any mRNAs ranging from a few hundred nucleotides to kilobases in length as cost effectively and quickly as possible without compromising on quality. If you have any special requirements in GMP-grade mRNA services, please feel free to contact us. We are looking forward to working together with your attractive projects.

Genomic engineering in cell lines is a versatile tool for studying gene function, designing diseases models, biopharmaceutical research, drug discovery and many other applications. CRISPR (Clustered Regulatory Interspaced Short Palindromic Repeats)/Cas9 systems is a newly developed yet the most popular method for genome editing. It has been widely used in current biology, functional genome screening, cell-based human hereditary disease modeling, epigenomic studies and visualization of cellular processes.
https://www.creative-biogene.c....om/Services/Plasmid-

The Rosa26 locus on mouse chromosome 6 is often used to integrate transgenic structures to achieve ubiquitous or conditional gene expression in mice and is considered to be one of the ideal locations for knockin targeted genes. The DNA fragments placed at the Rosa26 site are very safe and stable. Using the classical gene targeting method, obtain a gene knockin mouse at Rosa26 always takes one year or more. With the application of CRISPR/Cas9-mediated knockin technology, large DNA fragments can be accurately and efficiently inserted into the Rosa26.

CRISPR/Cas9 PlatformCB, a professional gene-editing technology services company, has extensive experience in the application of CRISPR/Cas gene-editing technology and has successfully knocked out/knocked specific genes in >300 mice. We guarantee to provide you with at least 2 Founder mice or 3 F1 mice and complete them within 3-5 months.
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