Sildenafil citrate inhibits the enzyme PDE5, which is responsible for breaking down cyclic guanosine monophosphate (cGMP). By preventing this breakdown, sildenafil enhances the effects of cGMP, leading to improved blood flow and a better erection.Onset of Action: Silditop 50 mg typically begins to work within 30 to 60 minutes after ingestion. Its effects can last for approximately 4 to 6 hours, providing a sufficient window for sexual activity.
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